The Atlanta Falcons (3-2) face the San Francisco 49ers (4-2) tonight in a Week 7 Sunday Night Football game at Levi’s Stadium in Santa Clara.
Atlanta enters on the rise, fueled by Bijan Robinson’s dominance on the ground and one of the NFL’s stingiest defenses. San Francisco, meanwhile, remains dangerous despite major injury setbacks, including the loss of linebacker Fred Warner and the ongoing absence of quarterback Brock Purdy.
Mac Jones starts in Purdy’s place once again — and he’s been solid filling in, throwing for over 340 yards in his last two starts. Jones and the 49ers offense will receive a boost with the return of tight end George Kittle.
Things to Watch
Falcons’ rushing attack vs. 49ers’ run defense
Atlanta leads the NFL in rushing (151.2 yards per game) and will test a San Francisco front seven missing its defensive anchor in Warner. The dual-threat Robinson’s vision and patience could be the deciding factor in sustaining drives.
49ers’ injury woes and offensive adjustments
San Francisco has been resilient but continues to play short-handed. Kittle returns to boost the passing game, but the offense must adapt without its usual rhythm.
Atlanta’s defense vs. San Francisco’s passing game
The Falcons’ defense ranks first in yards allowed per game (253.4). If they can pressure the 49ers’ backup quarterback and disrupt short-yardage plays, they could tilt the game in their favor.
Turnovers and tempo
With both teams limited offensively, turnovers and pace control will be crucial. Expect Atlanta to lean on ball control, while San Francisco looks for big plays from Christian McCaffrey to compensate for its injuries.
Predictions
This Sunday Night Football matchup feels like a toss-up. Atlanta’s running game and defense give it a real shot at the upset, especially against an injury-riddled 49ers team. But San Francisco’s home-field edge and system continuity can’t be discounted. If the Falcons can limit turnovers and dominate time of possession, they can pull off a statement win.
Projected Final Score: Falcons 24, 49ers 21
Injury Report
Atlanta Falcons
DE Jalon Walker
DB Billy Bowman Jr.
WR Ray-Ray McLoud
OT Jack Nelson
DE LaCale London
San Francisco 49ers
QB Brock Purdy
WR Ricky Pearsall
DL Yetur Gross-Matos
RB Jordan James
WR Jordan Watkins
OL Drew Moss
CB Upton Stout
How to Watch Falcons vs. 49ers
Kickoff for tonight’s Sunday Night Football game is set for 8:20 PM Eastern / 5:20 PM Pacific at Levi’s Stadium in Santa Clara.
The game airs live nationally on NBC. So you can tune in for free on your local NBC affiliate via antenna. NBC is also available at no additional cost through most cable, satellite, and live streaming packages.
You can also stream the game on the NBC, NBC Sports, and Peacock apps and websites.
If you’re a cord-cutter without an active livestreaming plan, you can watch the game for free by taking advantage of a free one-week trial of Peacock Premium Plus on Amazon Prime Video here.
Atlanta Falcons vs. San Francisco 49ers
Date: Sunday, October 19, 2025
Time: 8:20 PM Eastern / 5:20 PM Pacific
Venue: Levi’s Stadium, Santa Clara, CA
TV: NBC
Streaming: NBC and NBC Sports apps and website, Peacock, NFL+
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