The Buffalo Bills (4–1) face the Atlanta Falcons (2–2) tonight in a Week 6 Monday Night Football matchup at Mercedes-Benz Stadium in Atlanta.
Buffalo comes in looking to rebound from their first loss of the season to the New England Patriots at home on a game-winning field goal by the Pats with 15 seconds left. The Falcons, just off a bye, will be rested and ready to challenge, leaning on a top-tier defense and home-field energy.
5 Things to Watch
Bills’ defensive attrition & backfield issues
Buffalo will be missing several key defenders: Matt Milano, Damar Hamlin, and T.J. Sanders are all ruled out. That weakens their linebacker and safety rotation. On offense, tight end Dalton Kincaid and receiver Curtis Samuel are questionable, raising uncertainties in their passing game balance.
Falcons get Terrell back, but receivers limited
Atlanta’s cornerback A.J. Terrell practiced and is expected to return from a hamstring injury, which strengthens their secondary. However, WR Darnell Mooney is officially ruled out, limiting their receiving options.
Josh Allen’s dual-threat role vs. Falcons’ defense
Allen’s ability to run and throw makes him dangerous. With Buffalo’s defense weakened, Atlanta must pressure Allen and force him into mistakes.
Falcons’ defense vs. Buffalo’s run game
Buffalo’s ground attack — led by James Cook — will try to exploit Atlanta’s run defense, which has shown gaps. If the Falcons load the box, Buffalo may attack through the air; if not, Cook could break off chunks.
Turnovers & big-play swing potential
With both teams missing key pieces, the game could hinge on one or two critical turnovers or explosive plays. Whoever wins that battle may carry momentum late.
Injury Report
Buffalo Bills
LB Matt Milano — Out (Pectoral)
DT T.J. Sanders — Out (Knee)
S Damar Hamlin — Out (Pectoral)
TE Dalton Kincaid — Questionable (Oblique)
WR Curtis Samuel — Questionable (Neck / Ribs)
Atlanta Falcons
WR Darnell Mooney — Out (Hamstring)
CB Clark Phillips III — Out (Triceps / Illness)
DL LaCale London — Out (Triceps)
DL Ta’Quon Graham — Out (Calf)
CB Billy Bowman Jr. — Questionable (Knee / Hamstring)
CB Natrone Brooks — Questionable (Concussion / Shoulder)
Predictions
Even with defensive losses, Buffalo still boasts a well-rounded roster and playmakers who can exploit Atlanta’s gaps. The Falcons’ defense is strong, especially at home, and could force Buffalo into errors. But given the injuries in Buffalo’s secondary, expect the Bills to lean on the run, rely on Allen’s playmaking, and eke out a road win.
Projected Final Score: Bills 27, Falcons 24
How to Watch Bills vs. Falcons
Kickoff for tonight’s Monday Night Football game between the Buffalo Bills and Atlanta Falcons is set for 7:15 PM Eastern at Mercedes-Benz Stadium.
The game airs live on ESPN and streams on the ESPN app and website.
If you’re a cord-cutter without an active livestreaming plan, you can watch the game for free by taking advantage of free trials from DIRECTV Stream, Hulu + Live TV, Fubo TV, or YouTube TV.
YouTube TV even offers a 20-minute free preview, without having to register for a trial — if you just want to catch part of the game.
Buffalo Bills vs. Atlanta Falcons
Date: Monday, October 13, 2025
Time: 7:15 PM Eastern
Venue: Mercedes-Benz Stadium, Atlanta, GA
TV: ESPN
Streaming: ESPN app and website
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