The Kansas City Chiefs (2-2) travel to face the Jacksonville Jaguars (3-1) in a Week 5 Monday Night Football matchup at EverBank Stadium in Jacksonville.

After opening 0–2 for the first time in the Patrick Mahomes era — including a Week 2 loss to the Philadelphia Eagles — Kansas City’s early issues showed up in red-zone execution and timing before they steadied with back-to-back wins.

Last week’s 37–20 victory over the Baltimore Ravens featured a much sharper offensive showing (Mahomes 25-of-37 for 270 yards, 4 TDs) and the explosive return of WR Xavier Worthy, who caught 5 passes for 83 yards and added 38 rushing yards (including a 35-yard end-around) to lead the team in scrimmage yards.

But Worthy has been downgraded to questionable with shoulder and ankle concerns. That downgrade comes despite him being a full participant earlier in the week and suggests the move might be precautionary.

His absence would undoubtedly be a setback, removing one of the few true downfield threats Kansas City has had this season and limiting Mahomes’ ability to stretch defenses.

Mahomes has had to lean on his legs more than usual this year. Through four games, he’s rushed 22 times for 130 yards, averaging 5.9 yards per carry, leading the Chiefs. In games with tight windows or extra pressure, his mobility has been a key tool to keep drives alive and maintain offensive flexibility.

Jacksonville’s 3–1 start has been defense-first: the Jaguars have piled up a league-leading 13 takeaways through four games, fueling wins over the Carolina Panthers (26–10), Houston Texans (17–10), and San Francisco 49ers (26–21).

But the offense has been efficient too. Travis Etienne Jr. ranks fifth in the NFL in rushing with 394 yards on 65 carries (6.1 yards per attempt, three runs of 20+ yards, and three touchdowns), averaging 98.5 yards per game. His 124-yard performance at San Francisco set the tone, and he’s been a key balance point for Trevor Lawrence, keeping defenses honest.

A win tonight for Jacksonville would already match last season’s total (4–13).

4 Things to Watch

1. Mahomes vs. Jaguars’ turnover machine

Jacksonville leads the NFL in takeaways with nine on the year. The Chiefs must protect the ball early and prevent the Jaguars’ defense from dictating flow.

2. Jaguars’ pass rush / Travon Walker’s status

Walker is questionable after wrist surgery. If limited, Kansas City’s O-line may have more success in giving Mahomes time.

3. Kansas City’s receiving depth & Xavier Worthy injury

Worthy is listed as questionable with shoulder/ankle issues. His availability matters for spread and vertical threats.

4. Running games as tempo control

Jacksonville leans on Etienne’s explosive rushing. The Chiefs will respond with a shared backfield between Pacheco, Hunt, and even Mahomes on ground plays.

5. Jaguars’ receiver consistency / Lawrence’s timing

Lawrence is struggling with accuracy (58.3% completions, 4 INT). He and his receivers must clean up drops and synchronization to keep pace.

Predictions

Kansas City’s offense looks more cohesive, and with Mahomes fully healthy, they have the upside to break big plays. But Jacksonville’s defense is opportunistic, can flip momentum, and has had success controlling turnovers.

If the Chiefs can protect Mahomes and prevent costly mistakes, they likely pull away in the second half. But this could be tight until the fourth quarter.

Projected Final Score: Chiefs 28, Jaguars 24

Injury Report

Kansas City Chiefs

CB Kristian Fulton — Questionable (Ankle)

WR Xavier Worthy — Questionable (Shoulder / Ankle)

DT Omarr Norman-Lott — Questionable (Shoulder)

Jacksonville Jaguars

LB Yasir Abdullah — Out (Hamstring)

DE Travon Walker — Questionable (Wrist)

OT Wyatt Milum — Questionable (Knee)

How to Watch Chiefs vs. Jaguars

Kickoff for tonight’s Chiefs-Jaguars game is set for 8:15 PM Eastern / 7:15 PM Central at EverBank Stadium in Jacksonville.

The game airs live nationally on ABC with a simulcast on ESPN. So you can tune in for free on your local ABC affiliate via antenna. ABC is also available at no additional cost through most cable, satellite, and live streaming packages.

It also streams live on the ABC and ESPN apps and websites.

For the cord-cutters out there without an active livestreaming plan, you can watch the game for free by taking advantage of free trials from DIRECTV Stream, Hulu + Live TV, Fubo TV, or YouTube TV.

YouTube TV even offers a 20-minute free preview, without having to register for a trial — if you just want to catch part of the game.

Chiefs vs. Jaguars

Date: Monday, October 6, 2025

Time: 8:15 PM Eastern / 7:15 PM Central

Venue: EverBank Stadium, Jacksonville, FL

TV: ABC / ESPN

Streaming: ABC and ESPN apps and websites


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